BMB/MICRB 252: MOLECULAR AND CELL BIOLOGY II
Spring 2007 - Mon Wed Fri
10:10-11:00 102 Thomas
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(lec 1-15) |
(lec 16-44) |
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office: 452 N. Frear |
office: 429 S. Frear |
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phone: 863-8252 |
phone: 863-5555 |
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email: bfp2@psu.edu |
email: muk19@psu.edu |
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office hours: Mon.11:15-1:00 or by appoint. |
office hours: Mon.11:15-1:00 or by appoint. |
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lec |
date |
TOPIC |
READING: chpt(pgs) |
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Dr. Pugh's lectures |
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1 |
Jan. 17 |
Principles of cell communication |
15 (831-841) |
|
2 |
Jan. 19 |
Principles of cell
communication |
15 (842-852) |
|
3 |
Jan. 22 |
G-protein-linked receptors |
15 (852-871) |
|
4 |
Jan. 24 |
G-protein-linked receptors |
15 (852-871) |
|
5 |
Jan. 26 |
Enzyme-linked receptors |
15 (871-889) |
|
6 |
Jan. 29 |
Enzyme-linked receptors |
15 (871-889) |
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7 |
Jan. 31 |
Enzyme-linked receptors |
15 (871-889) |
|
8 |
Feb. 2 |
Signaling via proteolysis |
15 (893-899) |
|
9 |
Feb. 5 |
Signaling via proteolysis |
15 (893-899) |
|
10 |
Feb. 7 |
Review |
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|
11 |
Feb. 9 |
Chapter 15 |
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|
12 |
Feb. 12 |
Cytoskeleton assembly |
16 (907-929) |
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13 |
Feb. 14 |
Cytoskeleton regulation |
16 (929-948) |
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14 |
Feb. 16 |
Molecular motors |
16 (949-968) |
|
15 |
Feb. 19 |
Cell junctions |
19 (1066-1080) |
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Dr. Krasilnikova_*_s lectures |
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|
16 |
Feb. 21 |
Cell-cell adhesion |
19 (1080-1090) |
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17 |
Feb. 23 |
Extracellular matrix and
Integrins |
19 (1090-1118) |
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18 |
Feb. 26 |
The cell cycle |
17 (983-990) |
|
19 |
Feb. 28 |
Control of the cell cycle, programmed cell death |
17 (990-1014) |
|
20 |
Mar. 2 |
Mitosis |
18
(1027-1039, 1045-1056) |
|
21 |
Mar. 5 |
Review |
|
|
22 |
Mar. 7 |
Exam 2 |
Chapters
16, 17, 19 |
|
23 |
Mar. 9 |
Meiosis |
20
(1127-1139) |
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|
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Spring Break J
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|
24 |
Mar. 19 |
Germ cells
and fertilization |
20
(1139-1156) |
|
25 |
Mar. 21 |
Universal mechanisms
of animal development |
21
(1157-1169) |
|
26 |
Mar. 23 |
C.elegans:
developmental signals |
21
(1170-1177) |
|
27 |
Mar. 26 |
Drosophila:
mechanism of pattern formation |
21
(1177-1190) |
|
28 |
Mar. 28 |
Homeotic selector
genes. Experimental approaches in developmental biology |
21
(1190-1198) |
|
29 |
Mar. 30 |
Xenopus:
formation of an embryo driven by cell movements |
21
(1210-1222) |
|
30 |
Apr. 2 |
Derived
from ectoderm: epidermis and sensory epithelia |
22
(1259-1272) |
|
31 |
Apr. 4 |
Derived
from endoderm: airways and gut |
22
(1272-1283) |
|
32 |
Apr. 6 |
Derived
from mesoderm: |
22
(1283-1292, 1296-1311) |
|
33 |
Apr. 9 |
Review |
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|
34 |
Apr. 11 |
Exam 3 |
Chpts
20, 21, 22 |
|
35 |
Apr. 13 |
Cancer as
a microevolutionary process |
23
(1313-1326) |
|
36 |
Apr. 16 |
Preventable
causes of cancer |
23
(1326-1332) |
|
37 |
Apr. 18 |
Cancer-critical
genes |
23
(1333-1340) |
|
38 |
Apr. 20 |
Lymphocytes |
24
(1363-1374) |
|
39 |
Apr. 23 |
B-cells and
antibodies |
24
(1275-1392) |
|
40 |
Apr. 25 |
T-cells
and MHC proteins |
24
(1392-1410) |
|
41 |
Apr. 27 |
Helper T
cells and lymphocyte activation |
24
(1410-1420) |
|
42 |
Apr. 30 |
Introduction
to pathogens |
25
(1423-1434) |
|
43 |
Apr. 2 |
Innate immunity |
25
(1453-1462) |
|
44 |
Apr. 4 |
Review |
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|
|
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Exam 4 (during exam week - location to be
announced) |
Chapters
23, 24, 25 |
Required textbook: Alberts, et al., Molecular Biology of the Cell,
fourth edition. You should complete the reading assignment before class so that
you are familiar with the lecture material. This should aid you in
following each lecture.
Lecture notes: Overhead notes that are used in lectures and any
figures not in the Alberts text will be posted before class. You are
strongly encouraged to bring these lecture notes to class. Links to the notes that have been posted are
made by clicking on the lecture number in the schedule posted above.
Exams: Each exam will consist of 33 multiple choice
questions worth 3 points each. You will be asked to present your student
I.D. when you submit your exams. Scores will be reported by email to your
student account directly from University Testing Services.
Grades: The following table gives approximate assignments for
final grades. This scale is based on an overall class mean of 75% orhigher. If
the class mean is lower, the scale will be adjusted downward. It will not be adjusted upward. So for example, if you earn a
90% or higher you are guaranteed an A or A-.
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GRADE: |
PERCENTAGE: |
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A and A- |
90%-100% |
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B+, B and B- |
75%-90% |
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C+ and C |
60%-75% |
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D |
50%-60% |
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F |
lower than 50% |
Missed exams: Make up exams are either all essay questions or a
mixture of essay and short answer questions (instructor's discretion) and must
be taken prior to the next exam, or you will receive a zero. Whenever possible,
notify the instructor prior to the exam. Exams should only be missed for a
family emergency, accident, or serious illness.
No extra credit work will be
accepted. No exams will be
dropped.
Academic integrity: The students and instructors are bound bythe rules
and procedures on academic integrity set by the Eberly College of Science
Academic Integrity Committee. A complete listing of these policies can be found
at the following web site: http://www.science.psu.edu/academic/Integrity/index.html.
It is the student's responsibility to know
and abide by these policies. Failure to do so may result in sanctions or
expulsion.