BMB/MICRB 251:MOLECULAR AND CELLBIOLOGY I
Fall 2006 - Mon Wed Fri 12:20-1:10, 26
Hosler
|
Dr. Frank Pugh (lec 1-21) |
Dr. David Gilmour (lec 22-42) |
|
office: 452 N. Frear |
office: 403 S. Frear |
|
phone: 863-8252 |
phone: 863-8905 |
|
email: bfp2@psu.edu |
email: dsg11@psu.edu |
|
office hours: Mon.1:30-3:30 or by appointment |
office hours: Mon.1:30-3:30 or by appointment |
TA:
Lindsay
Dutko, lmd294@psu.edu, office hours Tues.
2-4 pm, 124 Life Sciences Bldg.
Notes for lectures 1-20 (PDF)
|
lec |
date |
TOPIC |
READING: chpt(pgs) |
|
Dr. Frank Pugh's lectures |
|||
|
1 |
Sept 6 |
Universal features of cells |
1 |
|
2 |
Sept 8 |
Chemistry of the cell |
2 |
|
3 |
Sept 11 |
Protein structure |
3 |
|
4 |
Sept 13 |
Proteins as enzymes |
3 |
|
5 |
Sept 15 |
Chromosome structure |
4 |
|
6 |
Sept 18 |
DNA replication mechanisms |
5 |
|
7 |
Sept 20 |
Initiation of DNA replication |
5 |
|
8 |
Sept 22 |
DNA repair |
5 |
|
9 |
Sept 25 |
DNA recombination |
5 |
|
Review session, September 26, 8:00 PM, place to be announced |
|||
|
10 |
Sept 27 |
Chapters1-5 |
|
|
11 |
Sept 29 |
Transcription |
6 |
|
12 |
Oct 2 |
RNA processing |
6 |
|
13 |
Oct 4 |
Translation |
6 |
|
|
Oct 6 |
No Class, Study Day! J |
|
|
14 |
Oct 9 |
Gene regulatory proteins |
7 |
|
15 |
Oct 11 |
Gene regulatory pathways |
7 |
|
16 |
Oct 13 |
Post transcriptional regulation |
7 |
|
17 |
Oct 16 |
Biochemical methods |
8 |
|
18 |
Oct
18 |
Molecular biology methods |
8 |
|
19 |
Oct
20 |
Protein structure/function methods |
8 |
|
20 |
Oct
23 |
Genetic & genomic methods |
8 |
|
Review session, October 24, 8:00 PM, place to be announced |
|||
|
21 |
Oct 25 |
Chapters
6-8 |
|
|
|
|||
|
Dr. David Gilmour's lectures |
|||
|
22 |
Oct 27 |
Visualizing cells |
9 |
|
23 |
Nov 1 |
Membrane structure and the lipid bilayer |
10 |
|
24 |
Nov 3 |
Membrane proteins |
10 |
|
25 |
Nov 6 |
Membrane proteins |
10 |
|
26 |
Nov 8 |
Membrane transport - carrier proteins and channels |
11 |
|
27 |
Nov 10 |
Channels and the membrane potential |
11 |
|
28 |
Nov 13 |
Nerve function |
11 |
|
29 |
Nov 15 |
Intracellular compartments and protein sorting |
12 |
|
30 |
Nov 17 |
Nuclear transport |
12 |
|
31 |
Nov 20 TUES! |
Mitochondrial, chloroplast, peroxisome import |
|
|
32 |
Nov 21 |
Covers Lec 22-31 |
|
|
|
Nov 22 |
NO CLASS - Thanksgiving |
|
|
|
Nov 24 |
NO CLASS - Thanksgiving |
|
|
33 |
Nov. 27 |
Endoplasmic reticulum, cotranslational transport |
12 |
|
34 |
Nov 29 |
||
|
35 |
Dec 1 |
ER to golgi to endosome to lysosome |
13 |
|
36 |
Dec 4 |
Endocytosis |
13 |
|
37 |
Dec 6 |
Exocytosis |
13 |
|
38 |
Dec 8 |
Energetics and energy conversion |
2 |
|
39 |
Dec 11 |
Mitochondria |
14 |
|
40 |
Dec 13 |
Mitochondria |
14 |
|
41 |
Dec 15 |
Chloroplast |
14 |
|
42 |
TBA |
Exam 4, time and place to be determined. |
Covers Lec 33-41 |
Required textbook: Alberts, et al., Molecular Biology of the Cell,fourth
edition. You should complete the reading assignment before class so that you
are familiar with the lecture material. This should aid you in following
each lecture.
Lecture notes: Overhead notes that are used in lectures and any
figures not in the Alberts text will be posted before class. You are
strongly encouraged to bring these lecture notes to class. Links to the notes that have been posted are
made by clicking on the lecture number in the schedule posted above.
Exams: Each exam will consist of 33 multiple choice
questions worth 3 points each. You will be asked to present your student
I.D. when you submit your exams. Scores will be reported by email to your
student account directly from University Testing Services.
Exam scores: As soon as the exams have been processed by
University Testing Services, your score will be reported by email to your
student access account. It is your responsibility to learn to use your
account and to check your posted scores for accuracy. Take your student ID
card to a CAC Help desk (215 Computer Building; 12 Willard) to learn how to use
your account. Call 863-2494 or 863-1035 for more information.
Grades: The following table gives approximate assignments for
final grades. This scale is based on an overall class mean of 75% or higher. If
the class mean is lower, the scale will be adjusted downward. It will not be adjusted upward. So for example, if you earn a
90% or higher you are guaranteed an A or A-.
|
GRADE: |
PERCENTAGE: |
|
A and A- |
90%-100% |
|
B+, B and B- |
75%-90% |
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C+ and C |
60%-75% |
|
D |
50%-60% |
|
F |
lower than 50% |
Missed exams: Make up exams are either all essay questions or a
mixture of essay and short answer questions (instructor's discretion) and must
be taken prior to the next exam, or you will receive a zero. When ever
possible, notify the instructor prior to the exam. Exams should only be missed
for a family emergency, accident, or serious illness, so written documentation
of the excuse is required.
No extra credit work will be accepted.
No exams will be dropped.
Academic integrity: The students and instructors are bound by the rules
and procedures on academic integrity set by the Eberly College of Science
Academic Integrity Committee. A complete listing of these policies can be found
at the following web site: http://www.science.psu.edu/academic/Integrity/index.html.
It is the student's responsibility to know
and abide by these policies. Failure to do so may result in sanctions or
expulsion.