Research Interest & Focus:

In our bodies, proliferating stem cells produce two types of daughter cells: one type keeps the stem cell identity, while the other type replenishes the pool of terminal differentiated somatic cells (Fig.1). Somatic cells express a distinct set of genes compared with their precursor stem cells. Further, the homeostasis of stem cell proliferation and differentiation keeps the balance of the number of dead and live cells. Over proliferation of stem cells or the failure of cell differentiation can produce large amount undifferentiated cells leading to cancers. See More...