Tan Lab

Pictures and QuickTime movies of macromolecules (mostly protein/DNA complexes)

	B-form DNA jpg file (72 kB)	B-form DNA QT movie (6.1 MB)

	434 represssor/DNA jpg file (62 kB) (helix-turn-helix motif)	434 repressor/DNA QT movie (10.8 MB)
	Aggarwal, Rodgers, Drottar, Ptashne & Harrison, Science, 242:899-907, 1988

	engrailed/DNA jpg file (36 kB) (homeodomain)	engrailed/DNA QT movie (7.5 MB)
	Kissinger, Liu, Martin-Blanco, Kornberg & Pabo, Cell, 63:579-590, 1990

Gcn4/DNA jpg file (69 kB)
(basic-zipper motif)

Gcn4/AP1 DNA QT movie (5.1 MB)

Gcn4/CREB DNA QT movie (4.8 MB)

Ellenberger, Brandl, Struh & Harrison, Cell, 71:1223-1237, 1992
Koenig & Richmond, JMB, 233:139-154, 1993

	zif268/DNA jpg file (40 kB) (zinc finger)	zif268/DNA QT movie (6.7 MB)
	Pavletich & Pabo, Science, 252:809-817, 1991

	SRF/DNA jpg file (65 kB) (MADS-box)	SRF/DNA QT movie (9.5 MB)
	Pellegrini, Tan & Richmond, Nature, 376:490-498, 1995

alpha2/MCM1/DNA jpg file (82 kB)
(homeodomain and MADS-box)

alpha2/MCM1/DNA QT movie (10.4 MB)

alpha2/MCM1/DNA extended QT movie to show crystal packing and chameleon sequence (27.2 MB)

Tan & Richmond, Nature, 391:660-666, 1998

	NFkB-p50/DNA jpg file (45 kB) (rel homology domain)	NFkB-p50/DNA QT movie (8.3 MB)
	Ghosh, Duyne, Ghosh & Sigler, Nature, 373:303-310, 1995 Mueller, Rey, Sodeoka, Verdine and Harrison, Nature, 373:311-317, 1995

	BamHI/DNA jpg file (90 kB) (restriction endonuclease)	BamHI/DNA QT movie (11.3 MB)
	Newman, Strzelecka, Dorner, Schildkraut & Aggarwal, Science, 269:656-663, 1995

	T7 DNA pol/thioredoxin/DNA jpg file (110 kB) (DNA polymerase)	T7 DNA pol/Trx/DNA QT movie (5.9 MB)
	Doublie, Tabor, Long, Richardson & Ellenberger, Nature 391:251-258, 1998

TBP dimer jpg file (68 kB)
(general transcription factors)

TBP monomer QT movie (8.2 MB)

TBP dimer QT movie (8.5 MB)

Nikolov, Hu, Lin, Gasch, Hoffmann, Horikoshi, Chua, Roeder & Burley, Nature, 360:40-46, 1992
Chasman, Flaherty, Sharp & Kornberg, PNAS, 90:8175-8178, 1993

	TBP/DNA jpg file (67 kB) (general transcription factors)	TBP/DNA QT movie (11.5 MB)
	Kim, Geiger, Hahn & Sigler, Nature, 365:512-520, 1993 Kim, Nikolov & Burley, Nature, 365:520-527, 1993

TFIIA/TBP/DNA jpg file (83 kB)
(general transcription factors)

TFIIA/TBP/DNA QT movie 1 (9.5 MB)

TFIIA/TBP/DNA QT movie 2 (8.9 MB)

Tan, Hunziker, Sargent & Richmond, Nature, 381:127-134, 1996
Geiger, Hahn, Lee & Sigler, Science, 272:830-836, 1996

	TFIIB/TBP/DNA jpg file (82 kB) (general transcription factors)	TFIIB/TBP/DNA QT movie (10.7 MB)
	Nikolov, Chen, Halay, Usheva, Hisatake, Lee, Roeder & Burley, Nature, 377:119-128, 1995

	nucleosome core particle jpg file (81 kB) (histone fold motif)	nucleosome core particle QT movie (11.6 MB)
	Luger, Maeder, Richmond, Sargent & Richmond, Nature, 389:251-260, 1997

Larger H.264 versions are available here.

This page is maintained by Song Tan: sxt30@psu.edu (814-865-3355)
Department of Biochemistry & Molecular Biology, 108 Althouse Lab, University Park, PA 16802

This page was last updated on April 7, 2008.

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