Projects:

Protein localization plays a vital role in cell division and differentiation. We are interested in how many proteins are localized in a bacterium, and how these proteins get to where they are supposed to go. We have used transposon mutagenesis to insert GFP randomly in the genome of C. crescentus, and we have screened these mutants for interesting GFP localization patterns. I am identifying the GFP fusion proteins that are localized, and determining the sequences that are important for their localization by site-directed mutagenesis. Ultimately, I hope to understand the underlying mechanisms for localization of specific proteins.

Publications:

  1. •Russell JH and Keiler KC (2007) “Peptide signals encode protein localization.” J Bacteriol 189: 7581-5.

  2. •Russell JH and Keiler KC (2008) “Screen for localized proteins in Caulobacter crescentus.” PLoS ONE 3: e1756. link

 

Jay Russell

  1. Graduate Student (BMMB)

  2. Cubs Fan


  4. BulletB.S. in Chemistry and Biochemistry, University of Southern Mississippi


  6. Address:   401 Althouse Lab

  7.                  University Park, PA 16802

  8. Phone:      (814) 863-0801

  9. Email:       jhr137@psu.edu

http://jb.asm.org/cgi/reprint/189/21/7581