Biochemistry and Molecular Biology 400: Molecular Biology of the Gene

Fall, 2002

209S Henderson South, 12:20-1:10 pm Mon, Wed, Fri

No.

Date

Topic

1

Aug 28

Part One: Genes, Nucleic Acids, Genomes and Chromosomes

1. Fundamental properties of genes

2

Aug 30

2. Structures of nucleic acids
 

Sep 02

LABOR DAY

3

Sep 04

  

4

Sep 06

3. Isolating and analyzing genes: Recombinant DNA technology, PCR,

And what you can learn from them

5

Sep 09

  

6

Sep 11

  

7

Sep 13

4. Genomes and chromosomes

8

Sep 16

Introduction to project

9

Sep 18

  

10

Sep 20

EXAMINATION #1

11

Sep 23

Part Two: Perpetuation and Variability of Genes

5. Replication I: Enzymology

12

Sep 25

  

13

Sep 27

Work on project, help in class

14

Sep 30

Work on project, help in class

15

Oct 02

6. Replication II: Start, stop, and control. Projects due

16

Oct 04

Guest lecturer: Dr. Craig Cameron

17

Oct 07

7. Mutability and repair of DNA

18

Oct 09

  

19

Oct 11

8. Recombination
 

Oct 14

FALL BREAK

20

Oct 16

  

21

Oct 18

9. Transposition

22

Oct 21

EXAMINATION #2

23

Oct 23

Part Three: Pathway of Gene Expression

10. Transcription: RNA polymerases

24

Oct 25

  

25

Oct 28

11. Transcription: Promoters

26

Oct 30

  

27

Nov 01

12. RNA processing

28

Nov 04

  

29

Nov 06

  

30

Nov 08

13. Genetic code

31

Nov 11

14. Translation

32

Nov 13

  

33

Nov 15

EXAMINATION #3

34

Nov 18

Part Four: Regulation of Gene Expression

15. Positive and negative control: lac operon

35

Nov 20

16. Transcriptional regulation by effects on RNA polymerase

36

Nov 22

  

37

Nov 25

17. Bacteriophage l

38

Nov 27

  
 

Nov 29

day after THANKSGIVING (no class)

39

Dec 02

18. Regulation AFTER initiation of transcription

40

Dec 04

19. Regulation of eukaryotic genes

41

Dec 06

  

42

Dec 09

  

43

Dec 11

20. Regulation by changes in chromatin structure

44

Dec 13

  
 

Dec 18

FINAL EXAM Wednesday, Dec. 18, 2:30-4:20 p.m.