Assignments for Part Four of BMB 400 Gene Regulation

Fall 2002

Date

Chpt

Pages

Questions/

Problems

Topic

Nov 18

15

609-624

15.1-15.6

Positive and negative regulation:

lac operon

Nov 20

16

629-639

16.1-16.4

Effects on RNA polymerase:

Binding constants, rate constants

Nov 22

 

640-651

16.5-16.8

Effects of inducers, repressors, activators

Nov 25

17

659-684

17.1-17.8

Bacteriophage l:

Transcriptional switches can regulate cellular decisions.

Nov 27

     

No class: Work on homework for Chpts 16 & 17

Nov 29

     

Day after THANKSGIVING

Dec 02

18

689-7001

18.1-18.5

Regulation after initiation: l antitermination, trp

Dec 04

19

703-712

19.1-19.7

Regulation of eukaryotic genes: Silencers, enhancers, activators

Dec 06

 

713-723

19.8-19.12

Functional domains of activators

Dec 09

 

724-731

19.13-19.16

Models and targets for activation

Dec 11

20

737-753

20.1, 20.2, 20.6

Regulation by changes in chromatin structure: Active chromatin

Dec 13

 

754-766, 771-772

20.3-20.5, 20.7

Models; remodeling activities

Themes in regulation

Dec 18

     

FINAL EXAM

2:30-4:20pm; WEDNESDAY

The final exam will be twice as long as the midterms. Half of it will cover Part Four, and half will cover the course comprehensively.