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Publications by Bernhard Lüscher

2007

Earnheart, J. C., C. Schweizer, F. Crestani, T. Iwasato, S. Itohara, H. Mohler, and B. Lüscher. GABAergic control of adult hippocampal neurogenesis in relation to behavior indicative of trait anxiety and depression states. J. Neurosci. 27:3845-3854.

Deng, L., J. Yao, C. Fang, N. Dong, B. Lüscher, and G. Chen. Sequential postsynaptic maturation governs the temporal order of GABAergic and glutamatergic synaptogenesis in rat embryonic cultures. J. Neurosci. 27:10860-10869.

2006

Qi, J., J. Yao, C. Fang, B. Lüscher, and G. Chen. Downregulation of tonic GABA currents following epileptogenic stimulation of rat hippocampal cultures. J. Physiol. 577:579-590.

Fang, C., L. Deng, C. A. Keller, M. Fukata, Y. Fukata, G. Chen, and B. Lüscher. GODZ-mediated palmitoylation of GABA(A) receptors is required for normal assembly and function of GABAergic inhibitory synapses. J. Neurosci. 26:12758-12768.

2005

Alldred, M. J., J. Mulder-Rosi, S. E. Lingenfelter, G. Chen, and B. Lüscher. Distinct gamma2 subunit domains mediate clustering and synaptic function of postsynaptic GABAA receptors and gephyrin. J. Neurosci. 25:594-603.

2004

Sinkkonen, S.T., B. Lüscher, H. Lüddens, and E.R. Korpi. Autoradiographic imaging of altered synaptic abg2 and extrasynaptic ab GABAA receptors in a genetic mouse model of anxiety. Neurochem. Int. 44:539-547.

Keller, C.A., X. Yuan, P. Panzanelli, M.L. Martin, M. Alldred, M. Sassoè-Pognetto, and B. Lüscher. The g2 subunit of GABA_A receptors is a substrate for palmitoylation by GODZ. J. Neurosci. 24:5881-5891.

Lüscher, B. and C.A. Keller. Regulation of GABA_A receptor trafficking, channel activity, and functional plasticity of inhibitory synapses. Pharmacol. Ther. 102:195-221.

Harvey, K., I.C. Duguid, M.J. Alldred, S.E. Beatty, H. Ward, N.H. Keep, S.E. Lingenfelter, B.R. Pearce, J. Lundgren, M.J. Owen, T.G. Smart, B. Lüscher, M.I. Rees, and R.J. Harvey. The GDP-GTP exchange factor collybistin: an essential determinant of neuronal gephyrin clustering. J. Neurosci. 24:5816-5826.

2003

Fritschy, J.-M., C. Schweizer, I. Brünig, and B. Lüscher. Pre- and post-synaptic mechanisms regulating the clustering of type A g-aminobutyric acid receptors (GABA_A receptors). Biochem. Soc. T. 31:889-892.

Schweizer, C., S. Balsiger, H. Bluethmann, I.M. Mansuy, J.-M. Fritschy. H. Mohler, and B. Lüscher. The g2 subunit of GABA_A receptors is required for maintenance of receptors at mature synapses. Mol. Cell. Neurosci. 24:442-450.

2002

Brunig, I., A. Suter, I. Knusel, B. Lüscher, and J.M. Fritschy. GABAergic terminals are required for postsynaptic clustering of dystrophin, but not of GABA-A receptors and gephyrin. J. Neurosci. 22:4805-4813.

Pannell, C., S.X. Simonian, G.E. Gillies, B. Lüscher, and A.E. Herbison. Hypothalamic somatostatin and growth hormone-releasing hormone mRNA expression depend upon GABA-A receptor expression in the developing mouse. Neuroendocrinology. 76:93-98.

Lüscher, B. GABA-A and GABA-C receptors: regulation of assembly, localization, clustering and turnover. In: Assembly and Targeting of Ion Channels. (J. Henley and S. Moss, eds.), pp. 192-218, Oxford University Press, Oxford, UK.

2001

Lüscher, B., and C.A. Keller. Ubiquitination, proteasomes and GABA-A receptors. Nature Cell Biol. 3:232-233.

Lüscher, B. , and J.-M. Fritschy. Subcellular localization and regulation of GABAA receptors and associated proteins. Intern. Rev. Neurobiol. 48:31-64.

2000

Lorez, M., D. Benke, B. Lüscher, H. Mohler, and J.A. Benson. Single-channel Properties of Neuronal GABA_A-receptors Lacking the g 2 Subunit. J. Physiol. 527:11-31.

Baer, K., C. Essrich, S. Balsiger, M.J. Wick, R.A. Harris, J.-M. Fritschy, and B. Lüscher. Rescue of g 2 Subunit-deficient Mice by Transgenic Overexpression of the GABA_A Receptor g 2S or g 2L Subunit Isoforms. Eur. J. Neurosci. 7:2639-43.

Wick, M.J., R.A. Radcliffe, B.J. Bowers, M.P. Mascia, B. Lüscher, R.A. Harris, and J.M. Wehner. Behavioral Changes Produced by Transgenic Expression of g 2L and g 2S Subunits of the GABA_A Receptor. Eur. J. Neurosci. 7:2634-2638.

Simonian, S.X., M.J. Skinner, W. Sieghart, C. Essrich, B. Lüscher, and A. Herbison. Role of GABA_A Receptor g 2 Subunit in the Development of the Gonadotropin-releasing Hormone Neurons in vivo. Eur. J. Neurosci. 12:3488-3496.

1999

Baer, K., C. Essrich, J.A. Benson, D. Benke, H. Bluethmann, J.M. Fritschy, and B. Lüscher. Postsynaptic Clustering of GABA_A Receptors by the g 3 Subunit in vivo. Proc. Natl. Acad. Sci. USA 96:12860-12865.

Crestani, F., M. Lorez, D. Benke, J.M. Fritschy, B. Lüscher, and H. Mohler. Impairment of GABA_A Receptor Clustering Results in Enhanced Anxiety Responses and a Cognitive Bias for Threat Cues. Nature Neurosci. 2:833-839.


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About Us Faculty Facilities Seminars Publications News and Events Outreach Links	Publications by Bernhard Lüscher 2007 Earnheart, J. C., C. Schweizer, F. Crestani, T. Iwasato, S. Itohara, H. Mohler, and B. Lüscher. GABAergic control of adult hippocampal neurogenesis in relation to behavior indicative of trait anxiety and depression states. J. Neurosci. 27:3845-3854. Deng, L., J. Yao, C. Fang, N. Dong, B. Lüscher, and G. Chen. Sequential postsynaptic maturation governs the temporal order of GABAergic and glutamatergic synaptogenesis in rat embryonic cultures. J. Neurosci. 27:10860-10869. 2006 Qi, J., J. Yao, C. Fang, B. Lüscher, and G. Chen. Downregulation of tonic GABA currents following epileptogenic stimulation of rat hippocampal cultures. J. Physiol. 577:579-590. Fang, C., L. Deng, C. A. Keller, M. Fukata, Y. Fukata, G. Chen, and B. Lüscher. GODZ-mediated palmitoylation of GABA(A) receptors is required for normal assembly and function of GABAergic inhibitory synapses. J. Neurosci. 26:12758-12768. 2005 Alldred, M. J., J. Mulder-Rosi, S. E. Lingenfelter, G. Chen, and B. Lüscher. Distinct gamma2 subunit domains mediate clustering and synaptic function of postsynaptic GABAA receptors and gephyrin. J. Neurosci. 25:594-603. 2004 Sinkkonen, S.T., B. Lüscher, H. Lüddens, and E.R. Korpi. Autoradiographic imaging of altered synaptic abg2 and extrasynaptic ab GABAA receptors in a genetic mouse model of anxiety. Neurochem. Int. 44:539-547. Keller, C.A., X. Yuan, P. Panzanelli, M.L. Martin, M. Alldred, M. Sassoè-Pognetto, and B. Lüscher. The g2 subunit of GABA_A receptors is a substrate for palmitoylation by GODZ. J. Neurosci. 24:5881-5891. Lüscher, B. and C.A. Keller. Regulation of GABA_A receptor trafficking, channel activity, and functional plasticity of inhibitory synapses. Pharmacol. Ther. 102:195-221. Harvey, K., I.C. Duguid, M.J. Alldred, S.E. Beatty, H. Ward, N.H. Keep, S.E. Lingenfelter, B.R. Pearce, J. Lundgren, M.J. Owen, T.G. Smart, B. Lüscher, M.I. Rees, and R.J. Harvey. The GDP-GTP exchange factor collybistin: an essential determinant of neuronal gephyrin clustering. J. Neurosci. 24:5816-5826. 2003 Fritschy, J.-M., C. Schweizer, I. Brünig, and B. Lüscher. Pre- and post-synaptic mechanisms regulating the clustering of type A g-aminobutyric acid receptors (GABA_A receptors). Biochem. Soc. T. 31:889-892. Schweizer, C., S. Balsiger, H. Bluethmann, I.M. Mansuy, J.-M. Fritschy. H. Mohler, and B. Lüscher. The g2 subunit of GABA_A receptors is required for maintenance of receptors at mature synapses. Mol. Cell. Neurosci. 24:442-450. 2002 Brunig, I., A. Suter, I. Knusel, B. Lüscher, and J.M. Fritschy. GABAergic terminals are required for postsynaptic clustering of dystrophin, but not of GABA-A receptors and gephyrin. J. Neurosci. 22:4805-4813. Pannell, C., S.X. Simonian, G.E. Gillies, B. Lüscher, and A.E. Herbison. Hypothalamic somatostatin and growth hormone-releasing hormone mRNA expression depend upon GABA-A receptor expression in the developing mouse. Neuroendocrinology. 76:93-98. Lüscher, B. GABA-A and GABA-C receptors: regulation of assembly, localization, clustering and turnover. In: Assembly and Targeting of Ion Channels. (J. Henley and S. Moss, eds.), pp. 192-218, Oxford University Press, Oxford, UK. 2001 Lüscher, B., and C.A. Keller. Ubiquitination, proteasomes and GABA-A receptors. Nature Cell Biol. 3:232-233. Lüscher, B. , and J.-M. Fritschy. Subcellular localization and regulation of GABAA receptors and associated proteins. Intern. Rev. Neurobiol. 48:31-64. 2000 Lorez, M., D. Benke, B. Lüscher, H. Mohler, and J.A. Benson. Single-channel Properties of Neuronal GABA_A-receptors Lacking the g 2 Subunit. J. Physiol. 527:11-31. Baer, K., C. Essrich, S. Balsiger, M.J. Wick, R.A. Harris, J.-M. Fritschy, and B. Lüscher. Rescue of g 2 Subunit-deficient Mice by Transgenic Overexpression of the GABA_A Receptor g 2S or g 2L Subunit Isoforms. Eur. J. Neurosci. 7:2639-43. Wick, M.J., R.A. Radcliffe, B.J. Bowers, M.P. Mascia, B. Lüscher, R.A. Harris, and J.M. Wehner. Behavioral Changes Produced by Transgenic Expression of g 2L and g 2S Subunits of the GABA_A Receptor. Eur. J. Neurosci. 7:2634-2638. Simonian, S.X., M.J. Skinner, W. Sieghart, C. Essrich, B. Lüscher, and A. Herbison. Role of GABA_A Receptor g 2 Subunit in the Development of the Gonadotropin-releasing Hormone Neurons in vivo. Eur. J. Neurosci. 12:3488-3496. 1999 Baer, K., C. Essrich, J.A. Benson, D. Benke, H. Bluethmann, J.M. Fritschy, and B. Lüscher. Postsynaptic Clustering of GABA_A Receptors by the g 3 Subunit in vivo. Proc. Natl. Acad. Sci. USA 96:12860-12865. Crestani, F., M. Lorez, D. Benke, J.M. Fritschy, B. Lüscher, and H. Mohler. Impairment of GABA_A Receptor Clustering Results in Enhanced Anxiety Responses and a Cognitive Bias for Threat Cues. Nature Neurosci. 2:833-839.
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