Publications by David S. Gilmour

2007

Zhang, Z., A. Klatt, A. J. Henderson, and D. S. Gilmour.  Transcription termination factor Pcf11 limits the processivity of Pol II on an HIV provirus to repress gene expression.  Genes & Dev. 21:1609-1614.

Wang, X., C. Lee, D. S. Gilmour, and J. P. Gergen.  Transcription elongation controls cell fate specification in the Drosophila embryos.  Genes & Dev. 21:1031-1036.

Zhang, Z., A. Klatt, D. S. Gilmour, and A. J. Henderson.  Negative elongation factor, NELF, represses human immunodeficiency virus transcription by pausing the RNA polymerase II complex.  J. Biol. Chem. 282:16981-16988.

2006

Zhang, A. and D. S. Gilmour. Pcf11 is a transcription termination factor in Drosophila that dismantles the elongation complex by bridging the CTD of RNA polymerase II to the nascent transcript. Mol. Cell 21:65-74.

2005

Zhang, Z., J. Fu, and D. S. Gilmour. CTD-dependent dismantling of the RNA polymerase II elongation complex by the pre-mRNA 3’ end processing factor, Pcf11. Genes & Dev. 19:1572-1580.

 
Wang, Y. V., H. Tang, and D. S. Gilmour. Identification in vivo of different rate-limiting steps associated with transcriptional activators in the presence and absence of a GAGA element. Mol. Cell. Biol. 25:3543–3552.
 
Wu, C-H., C. Lee, R. Fan, M. J. Smith, Y. Yamaguchi, H. Handa, and D. S. Gilmour. Molecular characterization of Drosophila NELF. Nucl. Acids Res. 33:1269–1279.

2004

Zhang, Z., C.-H. Wu, and D.S. Gilmour. Analysis of polymerase II elongation complexes by native gel electrophoresis: Evidence for a novel carboxyl-terminal domain-mediated termination mechanism. J. Biol. Chem. 279:23223-23228.

2003

Wu, C.-H., Y. Yamaguchi, L.R. Benjamin, M. Horvat-Gordon, J. Washinski, E. Enerly, J. Larsson, A. Lambertsson, H. Handa, and D. Gilmour. NELF and DSIF cause promoter proximal pausing on the hsp70 promoter in Drosophila. Genes & Dev. 17:1402-1414.

2002

Leibovitch, B.A., Q. Lu, L.R. Benjamin, Y. Liu, D.S. Gilmour, and S.C. Elgin. GAGA factor and the TFIID complex collaborate in generating an open chromatin structure at the Drosophila melanogaster hsp26 promoter. Mol. Cell. Biol. 22:6148-6157.

2001

Wu, C.-H., L. Madabusi, H. Nishioka, P. Emanuel, M. Sypes, I. Arkhipova, and D.S. Gilmour. Analysis of core promoter sequences located downstream from the TATA element in the hsp70 promoter for Drosophila melanogaster. Mol. Cell. Biol. 21:1593-1602.

Pugh, B.F., and D.S. Gilmour. Genome-wide analysis of protein-DNA interactions in living cells. Genome Biol. 2:103.1-103.3.

2000

Tang, H., Y. Liu, L. Madabusi, and D.S. Gilmour. Promoter Proximal Pausing on the hsp70 Promoter in Drosophila Depends Upon the Upstream Regulator. Mol. Cell. Biol. 20:2569-2580.

1999

Cartwright, I.L., D.E. Cryderman, D.S. Gilmour, L.A. Pile, L.L. Wallrath, J.A. Weber, and S.C. Elgin. Analysis of Drosophila Chromatin Structure in vivo. Method. Enzymol. 304:462-96.

Cryderman, D.E., H. Tang, C. Bell, D.S. Gilmour, and L.L. Wallrath. Heterochromatic Silencing of Drosophila Heat Shock Genes Acts at the Level of Promoter Potentiation. Nucleic Acids Res. 27:3364-70.

1998

Benjamin, L.R. and D.S. Gilmour. Nucleosomes are not Necessary for Promoter-proximal Pausing in vitro on the Drosophila hsp70 Promoter. Nucleic Acids Res. 26:1051-1055.

1997

Weber, J.A., D.J. Taxman, Q. Lu, and D.S. Gilmour. The Molecular Architecture of the hsp70 Promoter after Deleting the TATA Box or the Upstream Regulatory Region. Mol. Cell. Biol. 17:3799-3808.

1996

Li, B., J.A. Weber, Y. Chen, A.L. Greenleaf, and D.S. Gilmour. Analysis of Promoter-Proximal Pausing by RNA Polymerase II on the hsp70 Heat Shock Gene Promoter in a Drosophila Nuclear Extract. Mol. Cell Biol. 16:5433-5443.

1995

Gilmour, D.S. UV Crosslinking of DNA-protein Complexes in vitro. Methods Mol. Cell Biol. 5:162-168.

Weber, J.A. and D.S. Gilmour. Genomic Footprinting of the hsp70 and Histone H3 Promoters in Drosophila Embryos Reveals Novel Protein-DNA Interactions. Nucleic Acids Res. 23:3327-3334.

1994

Gilmour, D.S., A.R.Buchman, and J.L. Workman. Transcriptional Regulation of a Chromatin Template. In: Transcription Mechanisms and Regulation. (R.C. Conaway and J.W. Conaway, eds.), pp. 5l5-534. Raven Press, New York.

Lu, Q., L.L. Wallrath, P.A. Emanuel, S.C.R. Elgin, and D.S. Gilmour. Insensitivity of the Preset hsp2 Chromatin Structure to a TATA Box Mutation in Drosophila. J. Biol. Chem. 269:15906-159ll.

Purnell, B.A., P.A. Emanuel, and D.S. Gilmour. TFIID Sequence-recognition of the Initiator and Sequences Further Downstream in Drosophila Class II Genes. Genes Dev. 8:830-842.

Sypes, M.A. and D.S. Gilmour. Protein/DNA Crosslinking of a TFIID Complex Reveals Novel Interaction Downstream of the Transcription Start. Nucleic Acids Res. 22:807-8l4.

1993

Purnell, B.A. and D.S. Gilmour. Contribution of Sequences Downstream of the TATA Element to a Protein-DNA Complex Containing the the TATA-Binding Protein. Mol. Cell. Biol. l3:2593-2603.

Emanuel, P.A. and D.S. Gilmour. Transcription Factor TFIID Recognizes DNA Sequences Downstream of the TATA Element in the Hsp 70 Heat Shock Gene. Proc. Natl. Acad. Sci. USA 90:8449-8453.

1991

Gilmour, D.S., A.E. Rougvie, and J.T. Lis. Protein-DNA Cross-Linking as a Means to Determine the Distribution of Proteins on DNA in Vivo. Methods Cell Biol. 35:369-381.